Changes to Systemic Function
|
Body System
| Predicted Change from Sympathectomy
| Empirical Status
|
thermoregulation
|
loss of upper body sweating + loss of selective brain cooling = trouble staying cool
loss of surface vasoconstriction + loss of deep tissue vasodilation + decreased fat burning = trouble staying warm
increased upper body skin temperature = false messages from thermo-receptors |
thermal Images.
Goldstein’s (NINDS) core-body temperature study (not yet published)
shows significant problems maintaining core body temperature against
both hot and cold .
Nielson website listing “Heat Intolerance” among side effects.
anecdotal complaints of heat and cold intolerance abound. |
exercise capacity
| reduced cardiac output + reduced baroreflex
+ diminished lung volume + reduced evaporative cooling + inability to
redistribute blow flow into deep muscle = reduced exercise capacity
| reductions in every measure: cardiac index, heart rate, mean
arterial pressure, rate–pressure product, stroke index,
Changes_to_Systemic_Function%2C_part_ vascular resistance. “significant
reduction in baroreflex response to exercise”.
more studies needed
|
endocrine function
| lowered blood catecholamines
| confirmed
|
mental and emotional
| Loss of body-state changes in response to
strong emotion + Loss of feedback signal to brain = Reduced subjective
experience of emotion
Loss of sympathetic tone to cerebral artery + lowered blood catechols + loss of selective brain cooling = lowered alertness
| Critchley, et. al. report “Changes in bodily states, particularly
those mediated by the autonomic nervous system, are crucial to ongoing
emotional experience”.
Telaranta reports significant reduction in “fear” and “alertness” in studies of ETS on mental patients.
|
lack of informed consent + disturbing physical condition = profound anger + depression = suicide, suicidal ideation
| one confirmed U.S. ETS suicide, anecdotal reports abound |
immune function
| decreased tumor necrosis factor = increased tumors
| unstudied
|
decreased immune response + decreased blood cathechols = slow healing
| confirmed in rat skin, no human studies
|
body fat
| reduction in exercise capacity + reduced fat burning = increase in fat cell number + increase in fat cell size
| confirmed in rats, no human studies
|