Wednesday, May 29, 2013

Table 1



Changes to Individual Effectors in the Denerverd Area
Effector Sympathetic Effect Parasympathetic
Effect (if any)
Predicted Change From Sympathectomy Empirical Status
heart increase heart rate decrease heart rate reduced heart rate confirmed
increase heart contraction strength decrease heart contraction strength reduced heart contraction strength not studied
increase cardiac response to exercise decrease cardiac response to exercise reduced cardiac response to exercise confirmed
baroreflex increase heart rate decrease heart rate decreased baroreflex control of heart rate confirmed
blood vessels Constrict surface blood vessels
-
loss of vasoconstriction confirmed
Dilate deep blood vessels via NO release
-
Loss of NO modulated vasodilation confirmed
lungs dilate bronchial tubes constrict bronchial tubes Diminished lung volume confirmed
facilitate CO2 transfer
-
reduced CO2 transfer confirmed
sweat glands Secrete sweat
-
anhidrosis confirmed
arrector pili muscles goose bumps/physical pleasure
-
loss of goosebumps/physical pleasure not studied
muscles release nitric oxide (NO), dilate muscular blood vessels
-
loss of NO release, atrophy, fiber splitting, necrosis, phagocytosis, fibrosis confirmed in rabbits, no human studies
sensory nerves modulate sensitivity, physical pleasure
-
reduced tactile sensitivity confirmed
adipose tissue inhibit fat cell creation
-
increased fat cell number confirmed in hamsters, no human study
stimulate lipolysis (fat burning) stimulate lipogenisis (fat storage) decreased fat burning, increased fat cell size confirmed in hamsters, no human study
bone inhibit bone resorption stimulate bone resorption increased bone resorption confirmed in rats, no human study
inhibit interluken 1 alpha production
-
increased interluken 1 alpha production confirmed in rats, no human study
stimulate tumor necrosis factor (TNF) production
-
decreased TNF production confirmed in rats, no human study
thyroid facilitate iodide uptake
 ?
reduced iodide uptake confirmed in rats, no human studies
increase thyroid weight
 ?
loss of thyroid weight confirmed in rats, no human studies
increase thyroid metabolism generally
 ?
hypothyroidism unstudied